Tenofovir alafenamide Impurity 51 CAS 2126010-02-2(Free Base)
| CAS No. | 2126010-02-2(Free Base) |
| Molecular Formula | C16H20N5O4P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tenofovir alafenamide Impurity 51 (CAS 2126010-02-2(Free Base)), a pharmacopoeial impurity reference standard (molecular formula C16H20N5O4PC4H4O4, MW 493.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Tenofovir alafenamide Impurity 51 (C16H20N5O4PC4H4O4) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tenofovir alafenamide Impurity 51 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H20N5O4P C4H4O4 |
| Molecular Weight | 493.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Vancomycin EP Impurity H (CAS 357396-41-9)
- chondroitin sulfate impurity G (CAS CATO-C4X-32817)
- (R,R)-Moxifloxacin Impurity 112 (CAS CATO-C4X-1074112)
- 4-(3-Chlorobenzyl)-3,4-dihydrothieno[3,2-f][1,4]thiazepin-5(2H)-one (CAS 478247-18-6)
- 6-(Aminomethyl)-4-cyclopropoxypicolinic acid (CAS 1243381-61-4)
- n-Cyclopropyl-2-((3-fluorophenyl)amino)acetamide (CAS 923256-28-4)
- 6-tert-Butyl-3-(4-methoxybenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine (CAS 793678-86-1)
- 1-Cyclohexyl-4-methylbenzene (CAS 4501-36-4)
- 1-Benzoyl-3-(5-chloro-2-hydroxyphenyl)thiourea (CAS 815612-78-3)
- Gastric Inhibitory Polypeptide (human) (CAS 100040-31-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com